Medical and Psychological Evaluation
This is the initial stage when you are thinking of becoming an egg donor. To move further you are required to contact the clinic with whom you have decided to do egg donation. Once your application is acceptable then you will have to undergo medical and psychological evaluation. If medical team get satisfied with the reports then you will need to visit the clinic to understand how further tasks will take place.
- Detailed evaluation of her and her family history with genetic history is taken.
- We ask for any major diseases, any illness, any surgery, her obstetrics history (i.e about her deliveries and mode of it, any complication.
- Her habits like dietary habits, any habit of smoking or alcohol.
- Her personal hygiene etc.
In examination we evaluate her for physical characteristics
- Her appearance
- Skin colour
- Colour of eyes
- Hair colour
- Hair type
- Nutritional status
- Her personal hygiene
- Economical status
- Family background
- Economical Status of her husband etc.
- Her habits
- Educational status
Once she qualifies all these criteria, we involve her husband and if needed her family members too. We explain them the whole procedure.We do her ultrasound examination for pelvic organs. Then we try to improve her nutritional status. We prescribe hematinics and multivitamins to her.
PRE TREATMENT EVALUATION
It will be necessary for the egg donor to undergo a thorough medical examination. This includes:
- A pelvic exam.
- Blood draw to check hormone levels and to test for infectious diseases, and
- An ultrasound to examine her ovaries, uterus and other pelvic organs.
In addition, she will be referred to a psychologist who will evaluate if the donor is mentally prepared to undertake and complete the process. These evaluations are necessary to ensure that the egg donor is fully prepared and capable of completing an egg donation cycle, safely and successfully. These evaluations will be done at no cost to the donor.
Blood tests and Genetic tests to be performed on donor
Following blood tests are performed on a donor:
- Mantoux test
- VDRL (Venereal Decease Research Laboratory)
- PRL (Prolactin)
- TSH (Thyroid Stimulating Hormone, thyroid function test)
- CBC (complete blood count)
- ESR (erythrocyte sedimentation rate)
- Blood Group and Rh Typing
- HIV (human immunodeficiency virus)
- RBS (Random Blood Sugar)
- HCV (Hepatitis C Virus)
- SGPT (liver function test)
- Serum Creatinine
- Urine routine and microscopy
DONOR GENETIC SCREENING
Current list of genetic screening tests performed on our donors:
THALASSEMIA (Hb Electrophoresis)
Regardless of ethnicity, all donors undergo a blood test called a complete blood count. This is a screening test that looks at the size, shape and amount of a blood cells. This type of screening will detect some, but not all, individuals who carry alterations in their hemoglobin that could cause the genetic conditions alpha-thalassemia or beta-thalassemia in their offspring. The thalassemias are autosomal recessive genetic disorders that are part of a spectrum of diseases called the hemoglobinopathies, a group of illnesses that affect hemoglobin. Individuals affected with thalassemia generally have
- Severe anemia
- May require frequent blood transfusions
- Other medical surveillance
- Shortened lifespan
- Fetal demise or death in infancy.
The following carrier screening is performed on donors with any African ancestry:
SICKLE CELL DISEASE:
Sickle Cell Disease (SCD) is an autosomal recessive condition that is more common and more seen in certain subgroups of Indian population . Sickle cell disease is part of a spectrum of disorders called the hemoglobinopathies, a group of illnesses that affect hemoglobin. Individuals affected with SCD can have painful Joint, bone pain, and are at increased risk for strokes, infections and organ damage.
Other genetic testing that may have been performed on donors
This test is done on a donor only on request by a couple if they have been any carrier of disease .A chromosome analysis will only give us information about the number and structure of the chromosomes present. It will not give us information about specific genes. Infrequently, healthy and normal individuals carry chromosome rearrangements that are referred to as balanced translocations. Balanced translocations typically do not cause any health problems for the person with the translocation. However, people with balanced translocations are at increased risk for infertility, miscarriage and more serious chromosome problems in their children. As chromosome abnormalities are infrequent and inexpensive to test, all the donors are not tested for their chromosome; however, if a patient is willing to test the chromosome of a donor, we provide that facility . The Intended parent has to pay for the extra cost ,it doesn’t come in the package .
Once you got selected by intended parents for their cycle, you will be then required to sign the consent and agreement with the clinic and LETO.
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